2006 INDUCTEE Anthony Pawson, PhD Cells, Genetics & Genomics, Cancer

Anthony Pawson inducted into the Canadian Medical Hall of Fame

Edmonton, Alberta

Became head of the programme in Molecular Biology and Cancer at the Lunenfeld Research Institute

In 2002, he became its Director of Research.

Dr. Pawson developed the concept of signaling proteins and identified the Src homology 2 (SH2) domain as the prototypic protein-interaction module

This research on protein interactions transformed the thinking of how cells communicate.

Moved to Toronto to join the Department of Medical Genetics at the University of Toronto

At the same time, he became Senior Scientist at the Samuel Lunenfeld Research Institute, Mount Sinai Hospital in Toronto. He was one of the first appointments in the hospital’s molecular and developmental biology division.

After completing a postdoctoral research fellowship in the Department of Zoology, Dr. Pawson came to Canada

He became Assistant Professor in the Department of Microbiology and the University of British Columbia. At UBC, Dr. Pawson expanded his work on proteins to include the study of proteins that had the potential to cause cancer. His lab produced many important papers during this time.

After graduating from London University, Dr. Pawson travelled to the United States

He became a postdoctoral research fellow at the University of California, Berkeley in the Molecular and Virus Laboratory. There, Dr. Pawson began work on the protein products of avian retroviruses.