An icon in the field of allergy and immunology
Dr. Estelle Simons is renowned for career-long research on management of allergic diseases such as asthma, allergic rhinitis and anaphylaxis. As new medications were developed for these diseases over the years, she led a team that conducted innovative clinical pharmacology studies in patients of all ages, correlating blood concentrations with effects in body organs and confirming the scientific rationale for dosing. Most of these medications proved to be effective and safe and to this day they remain widely used around the world. With her colleagues in immunology, Dr. Simons also elucidated mechanisms associated with allergen sensitization and studied novel agents for immune modulation.