Father of the field of endocrinology
Recognized by the Canadian Institutes of Health Research as one of the most important Canadian discoveries, Dr. de Bold and his team’s isolation and sequencing of the cardiac polypeptide hormone ANF established that the heart has an endocrine function. Dr. de Bold demonstrated that through ANF, the heart modulates blood pressure, blood volume and cardiovascular growth at multiple levels. This seminal finding has served as the basis for many new avenues of research in cardiovascular physiology, with important clinical implications that have revolutionized patient care for conditions such as hypertension and heart failure.
