Jean-Lucien Rouleau has been recognized worldwide for his transformative contributions to cardiology, including translational scientific work in ventricular function, post-infarction ventricular remodelling, and neurohormonal activation. His leadership in clinical research culminated in the development of the life-saving medication sacubitril/valsartan, now routinely used to treat patients with chronic heart failure. As Director of the Institute of Circulatory and Respiratory Health, Dr.